Imatinib is used to treat?

Imatinib Mesylate is a Tyrosine Kinase inhibitor which finds use in the treatment of:

CCD: He's Good!

Chronic Myelomonocytic Leukemia
Chronic Myeloid Leukemia
Dermatofibrosarcoma protuberans

Hypereosinophilic Syndrome

Gastro-Intestinal Stromal Tumors

Drugs Causing SIADH

Certain drugs that precipitate the Syndrome of Inappropriate Ant Diuretic Hormone Secretion is highlighted by:

Very Old Case of PMS? No Trouble!

Very:

Vincristine

Vinblastine

Vasopressin/Desmopressin

Old:

Oxytocine (in very high doses)

Case:

Carbamazepine

Cyclophosphamide

Chlorpropamide

P:

Phenothiazines

M:

Mono Amine Oxidase Inhibitors

S:

Selective Serotonin Reuptake Inhibitors

No:

Nicotine

Trouble:

Tri Cyclic Antidepressants

drugs Undergoing Acetylation

Acetylation is a Phase 2 reaction that usually occurs in the following class of drugs:

SHIP

Sulfonamides
Hydralazine
Isoniazid
PAS

[Credits: AIIMS Ashish/Amit Aditya Publication]

Phase 2 Reactions

Phase 2 reactions add a conjugate to the moiety being metabolized. The different types of Phase 2 reactions are:

SMAGG

Sulfation

Methylation

Acetylation

Glucuronidation

Glycine Conjugation